Search Thermo Fisher Scientific
This gene encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains|The encoded protein responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism|Mutations in this gene are associated with a variety of human cancers, including hereditary cancers such as Li-Fraumeni syndrome|Alternative splicing of this gene and the use of alternate promoters result in multiple transcript variants and isoforms|Additional isoforms have also been shown to result from the use of alternate translation initiation codons from identical transcript variants (PMIDs: 12032546, 20937277)
BCC7; BMFS5; LFS1; P53; TRP53; tumor protein p53
100 µL